PTCD3

Entrez Summary: N/A
UniProt Summary: Mitochondrial RNA-binding protein that has a role in mitochondrial translation. {ECO:0000269|PubMed:19427859}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 183/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	10/28
blood	6/28
bone	6/26
breast	11/33
central nervous system	11/56
cervix	1/4
colorectal	4/17
esophagus	6/13
fibroblast	0/1
gastric	5/16
kidney	4/21
liver	7/20
lung	23/75
lymphocyte	3/16
ovary	2/26
pancreas	5/24
peripheral nervous system	2/16
plasma cell	2/15
prostate	0/1
skin	7/24
soft tissue	2/9
thyroid	0/2
upper aerodigestive	5/22
urinary tract	8/29
uterus	1/5

Expression Distribution

ribosomal small subunit binding
rRNA binding
ribosome
mitochondrial translational elongation
mitochondrial translational termination
translational termination
mitochondrial translation
translational elongation
cellular protein complex disassembly
mitochondrial gene expression
protein-containing complex disassembly
regulation of translation
translation
mitochondrial inner membrane
cellular component disassembly
regulation of cellular amide metabolic process
peptide biosynthetic process
posttranscriptional regulation of gene expression
amide biosynthetic process
peptide metabolic process
cellular amide metabolic process
mitochondrion
RNA binding
organonitrogen compound biosynthetic process
cellular nitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
protein-containing complex subunit organization
gene expression