SLC5A5

Gene Information
  • Official Symbol: SLC5A5
  • Official Name: solute carrier family 5 member 5
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 6528
  • UniProt: Q92911
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.[provided by RefSeq, Sep 2009].
  • UniProt Summary: Mediates iodide uptake in the thyroid gland.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2464
  • Expression level (log2 read counts): 1.81

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1