SNAP91

Entrez Summary: N/A
UniProt Summary: Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

ANTH
ENTH

extrinsic component of presynaptic endocytic zone membrane
synaptic vesicle budding from presynaptic endocytic zone membrane
clathrin heavy chain binding
synaptic vesicle budding
1-phosphatidylinositol binding
regulation of clathrin-dependent endocytosis
clathrin coat assembly
clathrin-dependent endocytosis
synaptic vesicle transport
synaptic vesicle localization
presynaptic endocytosis
synaptic vesicle endocytosis
synaptic vesicle recycling
clathrin-coated pit
clathrin-coated vesicle
SNARE binding
presynaptic membrane
phosphatidylinositol-4,5-bisphosphate binding
vesicle budding from membrane
regulation of receptor-mediated endocytosis
synaptic vesicle cycle
synaptic vesicle
vesicle-mediated transport in synapse
establishment of vesicle localization
vesicle localization
regulation of endocytosis
receptor-mediated endocytosis
vesicle organization
establishment of organelle localization
protein kinase binding
regulation of vesicle-mediated transport
endocytosis
organelle localization
import into cell
cellular protein-containing complex assembly
membrane organization
protein transport
peptide transport
protein-containing complex assembly
amide transport