SNRK

Entrez Summary: N/A
UniProt Summary: May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis. {ECO:0000250|UniProtKB:Q63553, ECO:0000269|PubMed:12234663, ECO:0000269|PubMed:15733851}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Phorbol-12-myristate-13-acetate 0.57μM R08 exp514	-2.58
WYE-354 6μM R02 exp90	1.76
Beta-Estradiol 0.55μM R07 exp425	1.81
Vemurafenib 6.6μM R02 exp89	1.9
Staurosporine 0.02μM R08 exp524	1.95
Wortmannin 5μM R00 exp38	2.17
TRAIL 50ng/ml R00 exp36	2.41
Mdivi-1 15μM R05 exp217	2.87

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Pkinase Tyr
Pkinase

magnesium ion binding
myeloid cell differentiation
protein serine/threonine kinase activity
hemopoiesis
hematopoietic or lymphoid organ development
immune system development
protein phosphorylation
phosphorylation
ATP binding
intracellular signal transduction