SPIDR

• Official Symbol: SPIDR
• Official Name: scaffold protein involved in DNA repair
• Aliases and Previous Symbols: N/A
• Entrez ID: 23514
• UniProt: Q14159
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity. {ECO:0000269|PubMed:23509288, ECO:0000269|PubMed:23754376}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 6125
• Expression level (log2 read counts): 5.76

Expression Distribution

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SPIDR Expression in NALM6 Cells: 5.76