STPG1

Entrez Summary: N/A
UniProt Summary: May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine. {ECO:0000269|PubMed:23028632}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Menadione 5μM R06 exp292	-2.14
Rapamycin 0.001μM R08 exp429	-1.89
Metformin 100 to 150μM on day4 R04 exp170	-1.75
Q15 2.7μM R02 exp79	1.73
Pimelic-diphenylamide-106 5μM R00 exp28	1.77
S-trityl-L-cysteine 0.5μM R05 exp243	1.79
Sulforaphane 9μM R08 exp526 no dilution day6	1.84
Cisplatin 0.35μM R06 exp273	1.87
Pyronaridine 1μM R06 exp295	1.91
Cryptotanshinone 12μM R05 exp227	2.11
Deguelin 0.15μM R05 exp209	2.46

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of protein homodimerization activity
positive regulation of mitochondrial membrane permeability involved in apoptotic process
mitochondrial outer membrane permeabilization involved in programmed cell death
positive regulation of mitochondrial membrane permeability
regulation of protein homodimerization activity
positive regulation of membrane permeability
regulation of mitochondrial membrane permeability involved in apoptotic process
apoptotic mitochondrial changes
regulation of mitochondrial membrane permeability
regulation of membrane permeability
positive regulation of protein binding
mitochondrial membrane organization
positive regulation of binding
mitochondrial transport
regulation of protein binding
regulation of binding
mitochondrion organization
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of cell death
molecular function
membrane organization
apoptotic process
programmed cell death
cell death
mitochondrion
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
positive regulation of molecular function