STRIP1

Entrez Summary: N/A
UniProt Summary: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. {ECO:0000269|PubMed:21834987}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 34/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	5/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	1/13
fibroblast	0/1
gastric	1/16
kidney	1/21
liver	4/20
lung	5/75
lymphocyte	0/16
ovary	4/26
pancreas	1/24
peripheral nervous system	0/16
plasma cell	1/15
prostate	0/1
skin	0/24
soft tissue	1/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	0/29
uterus	2/5

Expression Distribution

N1221
DUF3402

Rho GTPase binding
cortical actin cytoskeleton organization
cortical cytoskeleton organization
protein kinase binding
regulation of cell morphogenesis
actin cytoskeleton organization
actin filament-based process
molecular function
regulation of anatomical structure morphogenesis
cytoskeleton organization