TINAG

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Nifuroxazide 5μM R03 exp102	-2.05
6-Thio-2-deoxyguanosine 2μM R06 exp259	1.73
Hydroxyurea 15μM R06 exp289	1.73
Palbociclib 1μM R07 exp382	1.77
Disulfiram 4.3μM R06 exp281	2.45
Hippuristanol 0.12μM R08 exp489 no dilution day6	2.72

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Peptidase C1
Somatomedin B

polysaccharide binding
scavenger receptor activity
nucleotide binding
basement membrane
cysteine-type endopeptidase activity
endocytosis
import into cell
cell adhesion
biological adhesion
proteolysis
extracellular space
immune response
vesicle-mediated transport