TREML4

Entrez Summary: N/A
UniProt Summary: Positively regulates Toll-like receptor TLR7 signaling in macrophages. {ECO:0000269|PubMed:25848864}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of toll-like receptor 7 signaling pathway
regulation of toll-like receptor 7 signaling pathway
positive regulation of toll-like receptor signaling pathway
regulation of toll-like receptor signaling pathway
signaling receptor activity
positive regulation of innate immune response
positive regulation of response to biotic stimulus
regulation of innate immune response
positive regulation of defense response
positive regulation of multi-organism process
regulation of response to biotic stimulus
positive regulation of response to external stimulus
cell surface
regulation of defense response
innate immune response
regulation of multi-organism process
positive regulation of immune response
defense response to other organism
regulation of response to external stimulus
regulation of immune response
positive regulation of immune system process
response to other organism
response to external biotic stimulus
response to biotic stimulus
defense response
regulation of response to stress
positive regulation of signal transduction
regulation of immune system process
positive regulation of cell communication
positive regulation of signaling
immune response
extracellular region