TUBGCP2

Entrez Summary: N/A
UniProt Summary: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 730/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	28/28
blood	27/28
bone	25/26
breast	33/33
central nervous system	56/56
cervix	4/4
colorectal	17/17
esophagus	13/13
fibroblast	1/1
gastric	16/16
kidney	20/21
liver	19/20
lung	75/75
lymphocyte	16/16
ovary	26/26
pancreas	24/24
peripheral nervous system	16/16
plasma cell	15/15
prostate	1/1
skin	24/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	22/22
urinary tract	27/29
uterus	5/5

Expression Distribution

gamma-tubulin small complex
equatorial microtubule organizing center
microtubule nucleation by interphase microtubule organizing center
microtubule nucleation by microtubule organizing center
microtubule minus-end binding
gamma-tubulin complex
microtubule nucleation
gamma-tubulin binding
microtubule polymerization
microtubule polymerization or depolymerization
cytoplasmic microtubule
cytoplasmic microtubule organization
protein polymerization
spindle assembly
spindle pole
spindle organization
microtubule organizing center
meiotic cell cycle
supramolecular fiber organization
microtubule cytoskeleton organization
centrosome
microtubule-based process
mitotic cell cycle
organelle assembly
cellular protein-containing complex assembly
cell cycle process
cytoskeleton organization
cell cycle
reproductive process
reproduction
protein-containing complex assembly
protein-containing complex subunit organization
membrane