VAMP1

• Official Symbol: VAMP1
• Official Name: vesicle associated membrane protein 1
• Aliases and Previous Symbols: N/A
• Entrez ID: 6843
• UniProt: P23763
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014].
• UniProt Summary: Involved in the targeting and/or fusion of transport vesicles to their target membrane.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 17865
• Expression level (log2 read counts): 5.45

Expression Distribution

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VAMP1 Expression in NALM6 Cells: 5.45