WIF1

Entrez Summary: N/A
UniProt Summary: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Wnt-protein binding
positive regulation of fat cell differentiation
regulation of fat cell differentiation
negative regulation of Wnt signaling pathway
signaling receptor binding
cell-cell signaling by wnt
Wnt signaling pathway
regulation of Wnt signaling pathway
cell surface receptor signaling pathway involved in cell-cell signaling
cell surface
positive regulation of cell differentiation
cell-cell signaling
negative regulation of signal transduction
negative regulation of cell communication
negative regulation of signaling
positive regulation of developmental process
negative regulation of response to stimulus
regulation of cell differentiation
extracellular region