ZC3H7B

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Doxycycline 10μM R00 exp18	-2.39
PF-06409577 20μM R07 exp389	-2.24
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	-1.98
Wortmannin 5μM R00 exp38	-1.98
Nutlin-3A 1.6μM R06 exp294	-1.94
Mubritinib 0.2μM R02 exp65	-1.85
Docetaxel 0.002μM R01 exp45	-1.73
Erlotinib 10μM R05 exp216	1.84
SNS-032 15μM R08 exp443	2.15

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

production of miRNAs involved in gene silencing by miRNA
miRNA binding
dsRNA processing
production of small RNA involved in gene silencing by RNA
gene silencing by miRNA
posttranscriptional gene silencing by RNA
posttranscriptional gene silencing
gene silencing by RNA
gene silencing
regulation of gene expression, epigenetic
posttranscriptional regulation of gene expression
viral process
symbiotic process
interspecies interaction between organisms
RNA processing
RNA binding
RNA metabolic process
negative regulation of gene expression
gene expression