ZNF407

Entrez Summary: This gene encodes a zinc finger protein whose exact function is not known. It may be involved in transcriptional regulation. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
UniProt Summary: May be involved in transcriptional regulation.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 103/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	5/28
blood	2/28
bone	2/26
breast	10/33
central nervous system	0/56
cervix	0/4
colorectal	6/17
esophagus	0/13
fibroblast	0/1
gastric	3/16
kidney	2/21
liver	2/20
lung	10/75
lymphocyte	2/16
ovary	4/26
pancreas	5/24
peripheral nervous system	4/16
plasma cell	0/15
prostate	0/1
skin	3/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	6/22
urinary tract	5/29
uterus	2/5

Expression Distribution

RNA polymerase II core promoter sequence-specific DNA binding
histone methyltransferase complex
zinc ion binding
DNA-binding transcription factor activity, RNA polymerase II-specific