FAM50A

Entrez Summary: This gene belongs to the FAM50 family. The encoded protein is highly conserved in length and sequence across different species. It is a basic protein containing a nuclear localization signal, and may function as a DNA-binding protein or a transcriptional factor. [provided by RefSeq, Sep 2009].
UniProt Summary: May be a DNA-binding protein or transcriptional factor. {ECO:0000269|PubMed:9339379}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Bisphenol S 100μM R08 exp458	-2.39
Chloramphenicol 2μM R00 exp12	-2.08
CCCP 1μM R00 exp11	-1.96
PFI-3 10μM R03 exp144	1.73
SB202190 10μM R03 exp148	1.74
Nifurtimox 1μM R03 exp141	1.91
GSK343 3μM R03 exp124	1.91
Nicotinamide Riboside 100μM R03 exp139	1.91
Apcin 50 to 100μM on day4 R04 exp176	1.95
Dimethyl-Sulfoxide 1pc R03 exp120	2.17
Phenformin 20μM R03 exp143	2.21
MS023 2μM R03 exp134	2.22
AICAR 240μM R03 exp116	2.3

Global Fraction of Cell Lines Where Essential: 223/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	7/28
blood	15/26
bone	3/26
breast	7/30
central nervous system	22/49
cervix	1/4
colorectal	10/17
esophagus	4/11
fibroblast	1/1
gastric	7/14
kidney	3/18
liver	6/19
lung	16/72
lymphocyte	9/16
ovary	6/25
pancreas	5/22
peripheral nervous system	5/15
plasma cell	4/12
prostate	0/1
skin	7/20
soft tissue	3/9
thyroid	0/2
upper aerodigestive	2/22
urinary tract	13/28
uterus	0/5

Expression Distribution