NEDD1

Entrez Summary: N/A
UniProt Summary: Required for mitosis progression. Promotes the nucleation of microtubules from the spindle. {ECO:0000269|PubMed:19029337, ECO:0000269|PubMed:19509060}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Taxol 0.004μM R03 exp103	-2.82
Ammonium tetrathiomolybdate 10μM R08 exp448	-2.04
Artemisinin 50μM R08 exp450	-2
6-Thio-2-deoxyguanosine 2μM R06 exp259	-1.84
IU1-47 25μM R04 exp182	1.74
BI-6727 0.001μM R01 exp42	1.78
NFN1 1μM R03 exp100	1.78
Ethanol 0.003 R08 exp437	1.79
Alpha-Amanitin 0.5μM R00 exp5	2.01
JQ1 0.01μM R03 exp130	2.1
A-366 10μM R03 exp115	2.33

Global Fraction of Cell Lines Where Essential: 739/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	28/28
blood	28/28
bone	26/26
breast	33/33
central nervous system	56/56
cervix	4/4
colorectal	17/17
esophagus	13/13
fibroblast	1/1
gastric	16/16
kidney	21/21
liver	20/20
lung	75/75
lymphocyte	16/16
ovary	26/26
pancreas	24/24
peripheral nervous system	16/16
plasma cell	15/15
prostate	1/1
skin	24/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	22/22
urinary tract	29/29
uterus	5/5

Expression Distribution