POLR3GL

Entrez Summary: N/A
UniProt Summary: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. {ECO:0000269|PubMed:20154270}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
YM155 0.001μM R08 exp432	-2.06
Bisphenol A 100μM R06 exp269	1.72
BI-2536 0.001μM R01 exp41	1.82
Docetaxel 0.002μM R01 exp45	1.85
Combretastatin A4 0.002 to 0.003μM day4 R04 exp179	1.88
LB-100 4.1μM R02 exp72	1.91
2-Deoxy-D-glucose 800μM R05 exp214	2.02
Erlotinib 10μM R05 exp216	2.02
IU1-47 25μM R04 exp182	2.33

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution