ZMYND8
Gene Information
- Official Symbol: ZMYND8
- Official Name: zinc finger MYND-type containing 8
- Aliases and Previous Symbols: N/A
- Entrez ID: 23613
- UniProt: Q9ULU4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Bromodomain |
| PHD |
| PWWP |
| DUF3544 |
GO Terms
| regulation of postsynaptic density protein 95 clustering |
| positive regulation of dendritic spine maintenance |
| regulation of dendritic spine maintenance |
| regulation of postsynaptic membrane organization |
| regulation of postsynaptic density organization |
| lysine-acetylated histone binding |
| positive regulation of filopodium assembly |
| dendritic shaft |
| repressing transcription factor binding |
| modulation of excitatory postsynaptic potential |
| positive regulation of dendritic spine development |
| regulation of filopodium assembly |
| methylated histone binding |
| positive regulation of dendrite development |
| regulation of dendritic spine development |
| regulation of postsynapse organization |
| positive regulation of plasma membrane bounded cell projection assembly |
| protein N-terminus binding |
| regulation of nervous system process |
| dendritic spine |
| regulation of dendrite development |
| regulation of protein localization to membrane |
| regulation of plasma membrane bounded cell projection assembly |
| regulation of cell projection assembly |
| regulation of synapse organization |
| regulation of synapse structure or activity |
| transcription corepressor activity |
| protein domain specific binding |
| negative regulation of cell migration |
| negative regulation of cell motility |
| positive regulation of neuron projection development |
| negative regulation of cellular component movement |
| negative regulation of locomotion |
| positive regulation of neuron differentiation |
| positive regulation of cell projection organization |
| regulation of membrane potential |
| modulation of chemical synaptic transmission |
| regulation of trans-synaptic signaling |
| positive regulation of neurogenesis |
| regulation of neuron projection development |
| positive regulation of cellular component biogenesis |
| positive regulation of nervous system development |
| regulation of cellular protein localization |
| positive regulation of cell development |
| regulation of system process |
| regulation of neuron differentiation |
| regulation of plasma membrane bounded cell projection organization |
| regulation of cell projection organization |
| regulation of neurogenesis |
| zinc ion binding |
| regulation of cell migration |
| regulation of cell motility |
| regulation of cellular localization |
| regulation of nervous system development |
| regulation of cell development |
| regulation of cellular component biogenesis |
| positive regulation of cell differentiation |
| regulation of locomotion |
| regulation of cellular component movement |
| regulation of protein localization |
| positive regulation of cellular component organization |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| regulation of organelle organization |
| negative regulation of RNA metabolic process |
| positive regulation of developmental process |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| generation of neurons |
| negative regulation of biosynthetic process |
| neurogenesis |
| positive regulation of multicellular organismal process |
| regulation of cell differentiation |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 56/726
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 8/28 |
| bone | 2/25 |
| breast | 3/33 |
| central nervous system | 5/56 |
| cervix | 0/4 |
| colorectal | 1/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 1/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 3/75 |
| lymphocyte | 2/14 |
| ovary | 0/26 |
| pancreas | 1/24 |
| peripheral nervous system | 1/16 |
| plasma cell | 9/15 |
| prostate | 0/1 |
| skin | 5/24 |
| soft tissue | 1/7 |
| thyroid | 1/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 1/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 1081
- Expression level (log2 read counts): 6.51
Expression Distribution
ZMYND8 Expression in NALM6 Cells: 6.51
