GOSR2

Entrez Summary: This gene encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this gene may be involved in familial essential hypertension. [provided by RefSeq, Mar 2016].
UniProt Summary: Involved in transport of proteins from the cis/medial- Golgi to the trans-Golgi network. {ECO:0000269|PubMed:9349823}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 229/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	0/1
bile duct	5/28
blood	7/28
bone	8/26
breast	18/33
central nervous system	14/56
cervix	1/4
colorectal	7/17
esophagus	3/13
fibroblast	0/1
gastric	6/16
kidney	12/21
liver	5/20
lung	28/75
lymphocyte	7/16
ovary	8/26
pancreas	3/24
peripheral nervous system	3/16
plasma cell	6/15
prostate	1/1
skin	5/24
soft tissue	4/9
thyroid	0/2
upper aerodigestive	4/22
urinary tract	6/29
uterus	2/5

Expression Distribution