SNX27
Gene Information
- Official Symbol: SNX27
- Official Name: sorting nexin 27
- Aliases and Previous Symbols: N/A
- Entrez ID: 81609
- UniProt: Q96L92
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| RA |
| PDZ |
| PX |
GO Terms
| establishment of natural killer cell polarity |
| establishment of lymphocyte polarity |
| WASH complex |
| retromer complex |
| retrograde transport, endosome to plasma membrane |
| immunological synapse |
| phosphatidylinositol-3-phosphate binding |
| endosome to lysosome transport |
| natural killer cell activation |
| phosphatidylinositol binding |
| vesicle-mediated transport to the plasma membrane |
| lysosomal transport |
| establishment of cell polarity |
| vacuolar transport |
| early endosome membrane |
| establishment or maintenance of cell polarity |
| endosomal transport |
| early endosome |
| endosome |
| lymphocyte activation |
| leukocyte activation |
| intracellular protein transport |
| cell activation |
| protein transport |
| intracellular transport |
| peptide transport |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| establishment of localization in cell |
| nitrogen compound transport |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| PFKP | 0.408 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 3665
- Expression level (log2 read counts): 5.9
Expression Distribution
SNX27 Expression in NALM6 Cells: 5.9
