UBE2Q1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Etoposide 10μM R00 exp20	-2.47
Diepoxybutane 3μM R07 exp354	-2.35
Rotenone 20μM R00 exp34	-2.18
2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312	-2
Etoposide 1μM R00 exp19	-2
Hydroxyurea 100μM R07 exp329	-1.91
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	-1.71
Nicotinamide 2000μM R01 exp50	1.7
LLY-283 2.6μM R06 exp290	1.76
Nifuroxazide 5μM R03 exp102	1.78
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	1.8
Nicotine 3000μM R08 exp510	1.85
VER-155008 3.9μM R06 exp301	2.03
Cytochalasin-B 5μM R07 exp349	2.28
Ethanol 0.01 R05 exp234	2.59
Latrunculin-B 10μM R07 exp374	3
THZ531 0.225μM R08 exp444	3.68

Global Fraction of Cell Lines Where Essential: 12/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	2/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	1/15
prostate	0/1
skin	1/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	1/29
uterus	0/5

Expression Distribution