GABARAPL1

Gene Information
  • Official Symbol: GABARAPL1
  • Official Name: GABA type A receptor associated protein like 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 23710
  • UniProt: Q9H0R8
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000269|PubMed:16431922, ECO:0000269|PubMed:20404487}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 6499
  • Expression level (log2 read counts): -0.12

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1