GRAMD1A

Entrez Summary: N/A
UniProt Summary: May play a role in tumor progression. {ECO:0000269|PubMed:27585821}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
EPZ-5676 30μM R05 exp233	1.77
Vincristine 0.0005μM R04 exp190	1.92

organelle membrane contact site
endoplasmic reticulum-plasma membrane contact site
intrinsic component of endoplasmic reticulum membrane
cellular response to cholesterol
cholesterol transfer activity
cellular response to sterol
response to cholesterol
response to sterol
cholesterol binding
extrinsic component of cytoplasmic side of plasma membrane
sterol transport
cellular response to alcohol
organic hydroxy compound transport
response to alcohol
lipid transport
lipid localization
cellular response to lipid
cellular response to organic cyclic compound
response to lipid
response to organic cyclic compound
cellular response to oxygen-containing compound
response to oxygen-containing compound