MFAP1

Entrez Summary: N/A
UniProt Summary: May be required for pre-mRNA splicing. {ECO:0000250|UniProtKB:Q9W062}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
DABN racemic mixture R03 exp93	-2.08
Arsenate 40μM R06 exp264	-2
Actinomycin-D 0.001μM R00 exp3	-1.81
Calcium Ionophore 0.4μM R07 exp342	1.7
Radicicol 0.16μM R05 exp242	1.7
Deguelin 0.15μM R05 exp209	1.72
Epigallocatechin gallate 20μM R05 exp230	1.8
SGC2043 10μM R03 exp152	1.88
Quinacrine 2.5μM R03 exp146	1.91
Nicotinamide 1000μM R03 exp101	1.95
Nifuroxazide 1μM R01 exp51	1.96
Benzoate 10000μM R08 exp455	2.16
Bisphenol S 100μM R08 exp458	2.43

Global Fraction of Cell Lines Where Essential: 620/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	19/28
blood	22/28
bone	26/26
breast	25/33
central nervous system	49/56
cervix	2/4
colorectal	15/17
esophagus	12/13
fibroblast	1/1
gastric	16/16
kidney	15/21
liver	18/20
lung	64/75
lymphocyte	9/16
ovary	25/26
pancreas	20/24
peripheral nervous system	13/16
plasma cell	14/15
prostate	1/1
skin	20/24
soft tissue	8/9
thyroid	2/2
upper aerodigestive	14/22
urinary tract	24/29
uterus	5/5

Expression Distribution

microfibril
U2-type precatalytic spliceosome
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions
RNA splicing
mRNA processing
mRNA metabolic process
RNA processing
RNA binding
RNA metabolic process
extracellular region
gene expression