MTX1

Entrez Summary: N/A
UniProt Summary: Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Actinomycin-D 0.01μM R00 exp4	-2.15
Prochlorperazine 5.2μM R02 exp77	-2.03
LJH685 5μM R02 exp73	-1.94
MLN-4924 2μM R00 exp22	-1.9
Nifurtimox 1μM R03 exp141	-1.87
INK128 0.2μM R02 exp70	-1.76
Apcin 25μM plus proTAME 2μM R04 exp177	1.94
Epigallocatechin gallate 20μM R05 exp230	1.99
BML-284 0.09μM R08 exp460	2.07

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Tom37 C
Tom37

SAM complex
lactation
body fluid secretion
mammary gland development
gland development
regulation of body fluid levels
secretion
protein transport
peptide transport
amide transport
establishment of protein localization
nitrogen compound transport