NGDN

Entrez Summary: N/A
UniProt Summary: Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 12/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	1/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	2/21
liver	0/20
lung	2/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	2/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	0/29
uterus	1/5

Expression Distribution

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
small-subunit processome
maturation of SSU-rRNA
chromosome, centromeric region
ribosomal small subunit biogenesis
filopodium
rRNA processing
rRNA metabolic process
axon
ribosome biogenesis
regulation of translation
ncRNA processing
regulation of cellular amide metabolic process
dendrite
ribonucleoprotein complex biogenesis
ncRNA metabolic process
posttranscriptional regulation of gene expression
nucleolus
RNA processing
mitochondrion
RNA binding
RNA metabolic process
gene expression