ERP44

Gene Information
  • Official Symbol: ERP44
  • Official Name: endoplasmic reticulum protein 44
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 23071
  • UniProt: Q9BS26
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum. {ECO:0000269|PubMed:11847130, ECO:0000269|PubMed:14517240}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 13385
  • Expression level (log2 read counts): 6.33

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1