F8A1 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: F8A1
Official Name: coagulation factor VIII associated 1
Aliases and Previous Symbols: N/A
Entrez ID: 8263
UniProt: P23610
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: Not known. Possible housekeeping role.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Chloroquine 32μM R08 exp470	-2.47
Bafilomycin-A1 0.009μM R08 exp454	-2.4
Clomiphene 4.4μM R02 exp68	-2.38
BH1 1μM R04 exp169	-2.12
Vemurafenib 6.6μM R08 exp434	-1.92
3-Bromopyruvate 7μM R04 exp175	1.77
Radicicol 0.16μM R05 exp242	1.9

Global Fraction of Cell Lines Where Essential: 14/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	1/28
blood	1/26
bone	0/26
breast	2/30
central nervous system	0/49
cervix	0/4
colorectal	1/17
esophagus	0/11
fibroblast	0/1
gastric	1/14
kidney	0/18
liver	0/19
lung	1/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	1/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	2/22
urinary tract	0/28
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 3109
Expression level (log2 read counts): 3.49

Expression Distribution

Last modified: 2025/12/10 20:19
by 127.0.0.1