FAM13B

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Ethanol 0.01 R05 exp234	-2.61
ML-792 0.2μM R08 exp505	-2.27
Cryptotanshinone 12μM R05 exp227	-2.11
Sulforaphane 9μM R08 exp526 no dilution day6	-1.95
2-Deoxy-D-glucose 800μM R05 exp214	-1.92
A-395N 10μM R05 exp219	-1.71
DABN 20μM R00 exp17	1.81
Quinacrine 2.5μM R03 exp146	2.41

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

GTPase activator activity
regulation of small GTPase mediated signal transduction
positive regulation of GTPase activity
regulation of GTPase activity
positive regulation of hydrolase activity
regulation of hydrolase activity
positive regulation of catalytic activity
positive regulation of molecular function
regulation of intracellular signal transduction