JMJD8

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Cycloheximide 0.02μM R00 exp14	-1.82
Nicotinamide Riboside 100μM R03 exp139	-1.78
HMS-I1 1μM R01 exp46	1.72

regulation of pyruvate kinase activity
positive regulation of sprouting angiogenesis
regulation of sprouting angiogenesis
regulation of glycolytic process
regulation of carbohydrate catabolic process
regulation of purine nucleotide metabolic process
regulation of nucleotide metabolic process
regulation of ATP metabolic process
regulation of generation of precursor metabolites and energy
positive regulation of angiogenesis
positive regulation of vasculature development
positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of carbohydrate metabolic process
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of angiogenesis
endoplasmic reticulum lumen
regulation of vasculature development
regulation of small molecule metabolic process
regulation of transferase activity
regulation of catabolic process
endoplasmic reticulum
positive regulation of intracellular signal transduction
regulation of anatomical structure morphogenesis
positive regulation of developmental process
regulation of phosphorylation
positive regulation of signal transduction
positive regulation of multicellular organismal process
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
positive regulation of cell communication
positive regulation of signaling
regulation of intracellular signal transduction