SEZ6L

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Cidofovir 10μM R07 exp345	-1.73
Palbociclib 1μM R07 exp382	1.71

Sushi
CUB

synapse maturation
regulation of protein kinase C signaling
cerebellar Purkinje cell layer development
cerebellar cortex development
adult locomotory behavior
cerebellum development
metencephalon development
adult behavior
hindbrain development
locomotory behavior
developmental maturation
synapse organization
neuronal cell body
behavior
brain development
head development
endoplasmic reticulum membrane
central nervous system development
regulation of intracellular signal transduction