SLAIN1

Entrez Summary: N/A
UniProt Summary: Microtubule plus-end tracking protein that might be involved in the regulation of cytoplasmic microtubule dynamics, microtubule organization and microtubule elongation. {ECO:0000269|PubMed:21646404}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Hydroxychloroquine 30μM R08 exp490	-1.7
Geldanamycin 0.015 to 0.05μM on day4 R07 exp317	1.7
CHIR-124 0.04μM R06 exp272	1.84
FTY720 3μM R08 exp483	1.86
Docetaxel 0.002μM R01 exp45	1.9
Epothilone-B 0.0015μM R05 exp231	1.97
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	2.24
Ixabepilone 0.004 to 0.005μM on day4 R04 exp184	2.81
Taxol 0.004μM R03 exp103	3.34

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution