SLC43A3 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: SLC43A3
Official Name: solute carrier family 43 member 3
Aliases and Previous Symbols: N/A
Entrez ID: 29015
UniProt: Q8NBI5
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: Putative transporter. {ECO:0000250}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
IU1-C 25μM R04 exp183	-2.14
NMS-873 0.07μM R07 exp380	-1.9
Etoposide 0.3μM R05 exp199	-1.84
Phenformin 20μM R05 exp212	-1.8
Mubritinib 0.2μM R01 exp48	-1.73
UM0125461 0.74μM R02 exp84	2.2
Pterostilbene 16μM R02 exp78	2.55
6-Thio-2-deoxyguanosine 2μM R06 exp259	4.89
Amiloride 100μM R08 exp447	7.16

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 8598
Expression level (log2 read counts): 7.67

Expression Distribution

Last modified: 2025/12/10 20:19
by 127.0.0.1