SLC6A6

Entrez Summary: N/A
UniProt Summary: Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake. {ECO:0000269|PubMed:8382624}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

taurine:sodium symporter activity
alkanesulfonate transport
taurine transport
neurotransmitter:sodium symporter activity
xenobiotic transport
amino acid transmembrane transporter activity
sulfur compound transport
amino acid transmembrane transport
amino acid transport
organic acid transmembrane transport
carboxylic acid transmembrane transport
neurotransmitter transport
anion transmembrane transport
organic acid transport
carboxylic acid transport
cellular amino acid metabolic process
organic anion transport
anion transport
carboxylic acid metabolic process
ion transmembrane transport
oxoacid metabolic process
organic acid metabolic process
transmembrane transport
ion transport
integral component of plasma membrane
small molecule metabolic process
nitrogen compound transport