STRN3

Entrez Summary: N/A
UniProt Summary: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 2/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

WD40
Striatin

FAR/SIN/STRIPAK complex
armadillo repeat domain binding
negative regulation of intracellular estrogen receptor signaling pathway
Rho GTPase binding
protein phosphatase 2A binding
negative regulation of intracellular steroid hormone receptor signaling pathway
regulation of intracellular estrogen receptor signaling pathway
regulation of intracellular steroid hormone receptor signaling pathway
response to estradiol
calmodulin binding
protein-containing complex binding
neuronal cell body
dendrite
protein-containing complex
response to lipid
response to hormone
response to organic cyclic compound
Golgi apparatus
negative regulation of transcription, DNA-templated
negative regulation of nucleic acid-templated transcription
negative regulation of RNA biosynthetic process
negative regulation of signal transduction
negative regulation of RNA metabolic process
negative regulation of cell communication
negative regulation of signaling
negative regulation of cellular macromolecule biosynthetic process
negative regulation of nucleobase-containing compound metabolic process
negative regulation of macromolecule biosynthetic process
response to endogenous stimulus
negative regulation of cellular biosynthetic process
negative regulation of biosynthetic process
response to oxygen-containing compound
negative regulation of response to stimulus
negative regulation of gene expression