ZDHHC4

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
ABT-702 5μM plus Deferoxamine 11μM R07 exp321	1.75
Resminostat 0.5μM R07 exp393	1.92
R-DABN 8μM R03 exp111	2.01
Vinblastine 0.015μM R05 exp208	2.01
HMS-I1 10μM R06 exp256	2.32
Nocodazole 0.1μM R03 exp94	2.51
SB743921 0.001μM R05 exp244	2.57
Nocodazole 0.2μM R00 exp24	2.6
BI-6727 0.04μM R03 exp98	2.66
Nocodazole 0.2μM R02 exp64	2.77
DABN racemic mixture R03 exp93	3.41
Rotenone 2μM R00 exp33	3.71

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

peptidyl-L-cysteine S-palmitoylation
peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
protein-cysteine S-palmitoyltransferase activity
protein palmitoylation
peptidyl-cysteine modification
protein lipidation
lipoprotein biosynthetic process
lipoprotein metabolic process
protein targeting to membrane
protein acylation
establishment of protein localization to membrane
protein targeting
protein localization to membrane
peptidyl-amino acid modification
endoplasmic reticulum membrane
Golgi apparatus
intracellular protein transport
endoplasmic reticulum
organonitrogen compound biosynthetic process
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
establishment of localization in cell
nitrogen compound transport