ANKRD13C

Entrez Summary: N/A
UniProt Summary: Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER. {ECO:0000269|PubMed:20959461}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

protein retention in ER lumen
maintenance of protein localization in endoplasmic reticulum
regulation of receptor biosynthetic process
regulation of anoikis
maintenance of protein localization in organelle
maintenance of protein location in cell
maintenance of location in cell
maintenance of protein location
protein localization to endoplasmic reticulum
maintenance of location
signaling receptor binding
perinuclear region of cytoplasm
protein localization to organelle
endoplasmic reticulum membrane
endoplasmic reticulum
regulation of apoptotic process
regulation of programmed cell death
cellular protein localization
cellular macromolecule localization
regulation of cell death