APBB1IP

Official Symbol: APBB1IP
Official Name: amyloid beta precursor protein binding family B member 1 interacting protein
Aliases and Previous Symbols: N/A
Entrez ID: 54518
UniProt: Q7Z5R6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: N/A
UniProt Summary: Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin- induced promoter activities through AP1 and SRE. Mediates Rap1- induced adhesion. {ECO:0000269|PubMed:14530287, ECO:0000269|PubMed:15469846}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
T cell activation involved in immune response
lymphocyte activation involved in immune response
T cell receptor complex
lamellipodium
T cell activation
cytoskeleton
lymphocyte activation
positive regulation of cell adhesion
focal adhesion
leukocyte activation involved in immune response
cell activation involved in immune response
regulation of cell adhesion
leukocyte activation
cell activation
immune effector process
immune response