APOM

Entrez Summary: N/A
UniProt Summary: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. {ECO:0000269|PubMed:17525477, ECO:0000269|PubMed:19733574}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of plasma lipoprotein oxidation
discoidal high-density lipoprotein particle
regulation of plasma lipoprotein oxidation
spherical high-density lipoprotein particle
high-density lipoprotein particle clearance
high-density lipoprotein particle assembly
low-density lipoprotein particle
reverse cholesterol transport
high-density lipoprotein particle remodeling
antioxidant activity
very-low-density lipoprotein particle
high-density lipoprotein particle
cholesterol efflux
plasma lipoprotein particle assembly
plasma lipoprotein particle remodeling
protein-lipid complex remodeling
protein-containing complex remodeling
protein-lipid complex assembly
lipid transporter activity
plasma lipoprotein particle clearance
plasma lipoprotein particle organization
protein-lipid complex subunit organization
cholesterol transport
sterol transport
regulation of plasma lipoprotein particle levels
cholesterol homeostasis
sterol homeostasis
cellular oxidant detoxification
cellular detoxification
retinoid metabolic process
phospholipid binding
diterpenoid metabolic process
lipoprotein metabolic process
terpenoid metabolic process
detoxification
lipid homeostasis
isoprenoid metabolic process
response to glucose
organic hydroxy compound transport
response to hexose