CARNS1

Entrez Summary: N/A
UniProt Summary: Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine. {ECO:0000269|PubMed:20097752}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

carnosine biosynthetic process
homocarnosine synthase activity
carnosine synthase activity
carnosine metabolic process
histidine catabolic process
imidazole-containing compound catabolic process
histidine metabolic process
imidazole-containing compound metabolic process
FMN binding
aromatic amino acid family catabolic process
aromatic amino acid family metabolic process
cellular modified amino acid biosynthetic process
alpha-amino acid catabolic process
cellular amino acid catabolic process
cellular modified amino acid metabolic process
alpha-amino acid metabolic process
ATPase activity
carboxylic acid catabolic process
organic acid catabolic process
carboxylic acid biosynthetic process
organic acid biosynthetic process
cellular amino acid metabolic process
peptide biosynthetic process
heterocycle catabolic process
cellular nitrogen compound catabolic process
small molecule catabolic process
aromatic compound catabolic process
cellular component
organic cyclic compound catabolic process
drug metabolic process
amide biosynthetic process
peptide metabolic process
small molecule biosynthetic process
cellular amide metabolic process
carboxylic acid metabolic process
oxoacid metabolic process
organic acid metabolic process
organonitrogen compound catabolic process
organonitrogen compound biosynthetic process
ATP binding