ERMP1

Entrez Summary: N/A
UniProt Summary: Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures. {ECO:0000250|UniProtKB:Q6UPR8}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Bafilomycin-A1 0.009μM R08 exp454	-2.4
Pimelic-diphenylamide-106 0.5μM R00 exp27	-1.95
Nifurtimox 1μM R03 exp141	-1.83
Celastrol 0.12μM R05 exp225	-1.83
VE-822 0.04μM R06 exp300	1.78
Pifithrin-alpha 20μM R07 exp390	2.02
NN-Diethyl-meta-toluamide 500μM R08 exp438	2.53

Global Fraction of Cell Lines Where Essential: 2/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	1/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Peptidase M28
Peptidase M20

metallopeptidase activity
endoplasmic reticulum membrane
proteolysis
membrane