ESF1

Entrez Summary: N/A
UniProt Summary: May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 470/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	19/28
blood	21/28
bone	17/26
breast	16/33
central nervous system	31/56
cervix	3/4
colorectal	10/17
esophagus	9/13
fibroblast	1/1
gastric	12/16
kidney	12/21
liver	11/20
lung	54/75
lymphocyte	12/16
ovary	17/26
pancreas	19/24
peripheral nervous system	10/16
plasma cell	12/15
prostate	0/1
skin	16/24
soft tissue	7/9
thyroid	1/2
upper aerodigestive	4/22
urinary tract	13/29
uterus	3/5

Expression Distribution

rRNA processing
rRNA metabolic process
ribosome biogenesis
ncRNA processing
ribonucleoprotein complex biogenesis
ncRNA metabolic process
nucleolus
RNA processing
RNA binding
extracellular space
RNA metabolic process
gene expression