EVI5

Entrez Summary: N/A
UniProt Summary: Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis. {ECO:0000269|PubMed:16439210}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of cilium assembly
retrograde transport, endosome to Golgi
activation of GTPase activity
spindle
cytosolic transport
Rab GTPase binding
microtubule organizing center
regulation of plasma membrane bounded cell projection assembly
regulation of cell projection assembly
regulation of organelle assembly
endosomal transport
GTPase activator activity
positive regulation of GTPase activity
regulation of GTPase activity
cell division
intracellular membrane-bounded organelle
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
positive regulation of hydrolase activity
regulation of cellular component biogenesis
Golgi apparatus
intracellular protein transport
regulation of hydrolase activity
regulation of organelle organization
cell cycle
positive regulation of catalytic activity
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
positive regulation of molecular function
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport