FAM117A [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: FAM117A
Official Name: family with sequence similarity 117 member A
Aliases and Previous Symbols: N/A
Entrez ID: 81558
UniProt: Q9C073
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
LY2090314 0.003μM R08 exp499	-2.37
YM155 0.001μM R08 exp432	-2.17
LY2090314 0.003μM R08 exp500 no dilution day6	-2.13
Phenformin 20μM R05 exp212	1.71
Oligomycin-A 2μM R00 exp25	1.72
I-BRD9 4μM R07 exp365	1.73
BI-2536 0.0042μM R03 exp95	2.02
Wiskostatin 3μM R07 exp422	2.04
Wortmannin 0.5μM R00 exp37	2.17

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 12849
Expression level (log2 read counts): 5.26

Expression Distribution

Last modified: 2026/01/07 22:36
by 127.0.0.1