GORASP2

Entrez Summary: N/A
UniProt Summary: Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. {ECO:0000269|PubMed:10487747, ECO:0000269|PubMed:21515684}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

establishment of protein localization to plasma membrane
Golgi organization
protein localization to plasma membrane
protein localization to cell periphery
response to endoplasmic reticulum stress
establishment of protein localization to membrane
endomembrane system organization
protein localization to membrane
spermatogenesis
male gamete generation
Golgi membrane
gamete generation
organelle assembly
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
endoplasmic reticulum membrane
Golgi apparatus
multi-organism reproductive process
reproductive process
reproduction
cellular protein localization
cellular macromolecule localization
establishment of protein localization
cellular response to stress
membrane