IFNW1
Gene Information
- Official Symbol: IFNW1
- Official Name: interferon omega 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 3467
- UniProt: P05000
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Interferon |
GO Terms
| cytokine receptor binding |
| type I interferon receptor binding |
| positive regulation of peptidyl-serine phosphorylation of STAT protein |
| regulation of peptidyl-serine phosphorylation of STAT protein |
| natural killer cell activation involved in immune response |
| B cell proliferation |
| response to exogenous dsRNA |
| response to dsRNA |
| natural killer cell activation |
| T cell activation involved in immune response |
| lymphocyte proliferation |
| mononuclear cell proliferation |
| leukocyte proliferation |
| positive regulation of peptidyl-serine phosphorylation |
| B cell differentiation |
| lymphocyte activation involved in immune response |
| regulation of receptor signaling pathway via JAK-STAT |
| regulation of receptor signaling pathway via STAT |
| regulation of peptidyl-serine phosphorylation |
| cell cycle arrest |
| B cell activation |
| cytokine activity |
| defense response to virus |
| T cell activation |
| lymphocyte differentiation |
| response to virus |
| leukocyte differentiation |
| humoral immune response |
| lymphocyte activation |
| cell population proliferation |
| hemopoiesis |
| negative regulation of cell cycle |
| hematopoietic or lymphoid organ development |
| adaptive immune response |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| immune system development |
| cytokine-mediated signaling pathway |
| response to organic cyclic compound |
| leukocyte activation |
| defense response to other organism |
| cell cycle process |
| cellular response to cytokine stimulus |
| positive regulation of protein phosphorylation |
| positive regulation of phosphorylation |
| cell activation |
| response to nitrogen compound |
| immune effector process |
| response to cytokine |
| positive regulation of phosphate metabolic process |
| positive regulation of phosphorus metabolic process |
| regulation of cell cycle |
| positive regulation of protein modification process |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| cell cycle |
| regulation of protein phosphorylation |
| regulation of phosphorylation |
| extracellular space |
| positive regulation of cellular protein metabolic process |
| positive regulation of protein metabolic process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of protein modification process |
| immune response |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Resveratrol 16μM R03 exp147 | -2.01 |
| UMK57 0.6μM R03 exp107 | -1.87 |
| B02 10μM R08 exp453 | -1.75 |
| Bisphenol S 100μM R08 exp458 | 1.75 |
| Hypoxia 5%O2 R04 exp191 | 1.78 |
| Wortmannin 5μM R00 exp38 | 1.89 |
| Celastrol 0.12μM R05 exp225 | 2.32 |
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| HGC6.3 | 0.433 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 15273
- Expression level (log2 read counts): -0.23
Expression Distribution
IFNW1 Expression in NALM6 Cells: -0.23
