KIF3B

Entrez Summary: N/A
UniProt Summary: Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

kinesin II complex
plus-end kinesin complex
intraciliary transport particle B binding
mitotic centrosome separation
plus-end-directed vesicle transport along microtubule
plus-end-directed organelle transport along microtubule
centrosome separation
ATP-dependent microtubule motor activity, plus-end-directed
Rho GTPase binding
mitotic spindle assembly
spindle microtubule
positive regulation of cytokinesis
intraciliary transport involved in cilium assembly
vesicle transport along microtubule
anterograde axonal transport
ciliary tip
vesicle cytoskeletal trafficking
intraciliary transport
kinesin complex
axonal transport
axon cytoplasm
axo-dendritic transport
microtubule-based protein transport
protein transport along microtubule
microtubule motor activity
mitotic spindle organization
organelle transport along microtubule
centrosome cycle
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
positive regulation of cell division
regulation of cytokinesis
microtubule organizing center organization
antigen processing and presentation of exogenous peptide antigen via MHC class II
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
antigen processing and presentation of peptide antigen via MHC class II
spindle assembly
microtubule cytoskeleton organization involved in mitosis
determination of left/right symmetry
determination of bilateral symmetry
specification of symmetry