KRTAP5-7
Gene Information
- Official Symbol: KRTAP5-7
- Official Name: keratin associated protein 5-7
- Aliases and Previous Symbols: N/A
- Entrez ID: 440050
- UniProt: Q6L8G8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 4050
- Expression level (log2 read counts): -3.8