LRRC30

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Prochlorperazine 5.2μM R02 exp77	-1.86
GSK591 2.6μM R03 exp128	-1.78
Fluvastatin 2.2μM R06 exp282	-1.71
Tubastatin-A 2.5μM R07 exp417	1.97
Asunaprenir 3μM R07 exp336	2.1
PT-1 25μM R07 exp392	2.14
All-trans-Retinoic-Acid 40μM R07 exp334	2.18
Dimethyloxaloylglycine 11μM R07 exp314	2.24
BN82002 4μM R07 exp340	2.38
ABT-702 5μM plus Deferoxamine 11μM R07 exp321	2.43
PF-06409577 20μM R07 exp389	2.74

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

photoreceptor outer segment membrane
photoreceptor inner segment
protein serine/threonine phosphatase activity
protein dephosphorylation
dephosphorylation