M6PR

• Official Symbol: M6PR
• Official Name: mannose-6-phosphate receptor, cation dependent
• Aliases and Previous Symbols: N/A
• Entrez ID: 4074
• UniProt: P20645
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 2815
• Expression level (log2 read counts): 7.46

Expression Distribution

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M6PR Expression in NALM6 Cells: 7.46